Assessment is “the assessment of baseline function or status” and it should:
- be individualised to each patient
- include objective baseline measures of physical fitness, nutritional status and psychology
- be undertaken using validated assessment tools
Assessment in practice:
- undertaken by registered health and care professionals (registered, enhanced, advanced, consultant) or unregistered health and care professionals (supportive, assistive) through delegated authority
- implementation and effectiveness should be audited as part of a quality assurance and improvement framework
- a set of standardised assessment methods should be defined and used consistently
Physical Fitness
People gain and maintain physical fitness through movement. There are differences between the movement of physical activity and exercise.
Physical activity: “any bodily movement produced by skeletal muscles that results in energy expenditure.”
Exercise: “a subset of physical activity that is planned, structured, and repetitive and has, as a final or an intermediate objective, the improvement or maintenance of physical fitness.’’
Cardiopulmonary Exercise Testing
- dynamic assessment of the cardiopulmonary system at rest and during exercise
- usually performed on an upright or semi-recumbent stationary bike
- produces 9-panel plot and set of variables
- low values for anaerobic threshold and peak oxygen consumption are associated with poorer outcomes
6 Minute Walk Test (6MWT)
- requires no specialist equipment
- measures distance covered on a flat surface over 6 minutes
- self-paced, allowed to rest as needed
- average range in healthy adults is 400-700m
- an improvement of 50m post intervention is considered clinically important
- can identify people at higher risk of complications
Incremental Shuttle Walk Test (ISWT)
- 10m course walked at increasing pace
- similar to the “bleep test”
- achieving >400m correlates to a VO2 peak of >15ml/kg/min
Timed Up and Go (TUG) Test – Very Well Health
WHO Disability Assessment Schedule (WHODAS 2.0)
Brief fatigue inventory – FACIT- Fatigue
Nutrition
Cancer, or the effects of cancer treatments, can sometimes cause malnutrition and weight loss. Malnutrition is when the body is not getting enough vitamins, minerals and nutrients from the diet , such as protein, to keep healthy and maintain weight.
Reversing malnutrition and helping people living with cancer get the best nutrition is a vital part of prehabilitation.
Almost 50% of patients admitted to hospital are malnourished or at risk of malnutrition.
Subjective Global Assessment SGA
- Canadian Malnutrition Task Force
- Assessment includes taking a history of recent intake, weight change, gastrointestinal symptoms and a clinical evaluation
Patient Generated Subjective Global Assessment questionnaire (PG-SGA short form)
Blood Tests
- anaemia is a predictor of adverse post-operative outcomes
- measure B12 / folate / iron levels as indicated by sub-type of anaemia
- vitamin D deficiency has been associated with poorer post-operative outcomes
- albumin / prealbumin / zinc have been used as surrogate markers for malnutrition. They may be lowered in inflammatory states (including in patients with cancer) and not accurately reflect true protein state
Sarcopenia
- Sarcopenia is the progressive loss of muscle mass and is associated with poorer outcomes. It can be caused by a combination of lack of exercise and malnutrition
- Gold standard in a research setting is dual-energy X-ray absorptiometry (DXA) or bioelectrical impedance analysis (BIA) .
- In a clinical setting, cases are identified when a patient reports symptoms or signs of sarcopenia such as feeling weak, slow walking speed or difficulty rising from a chair.
- CT imaging of the psoas muscle can detect sarcopenia. CT scan images obtained as part of radiotherapy planning can also be used to detect sarcopenia.
Psychology and Psychosocial Health
Worry, fear and anxiety are amongst the most commonly reported concerns for people living with cancer at any stage in their journey from diagnosis, through treatment and after treatment ends. Many people are living with long term mental health problems after cancer treatment and for many, the fear of recurrence (cancer coming back) is an ever-present source of worry, fear and anxiety.
Some psychosocial consequences may be particularly severe, resulting in persistent mental health difficulties. Symptoms of post-traumatic stress disorder have been reported among 15–18% of female survivors of breast cancer and of lung cancer survivors, 31% were clinically depressed.
As with prehabilitation, most health and care professionals can provide level 1 emotional support as set out below.
Assessment
- Everyone should be able to recognise emotional distress
- Avoid causing psychological harm
- Know when to refer to a more specialist service
Intervention
- Communicate honestly and compassionately
- Treat patients with kindness and respect
- Establish and maintain supportive relationships
- Inform people with cancer and their carers about the emotional and support services
- available to them
Anxiety management can have a positive impact for these people. Relaxation techniques such as visualisation and mindfulness discussed earlier can be very helpful in this situation in making people feel more comfortable.
At a universal level no formal psychological assessments would be used.
At a targeted level assessment tools at Level 2 and 2 plus could include:
Patient Health Questionnaire- 9 (PHQ-9)
- The PHQ-9 is an assessment tool used frequently by healthcare professionals to help identify those most in need of support
- It is often used to monitor the severity of depression and response to treatment
- Is often used alongside GAD-7
- Explicitly asks about suicidal thoughts – therefore should be completed in a supportive environment with a practitioner who is skills and able to respond to this
Generalised Anxiety Disorder Assessment (GAD-7)
- Often used alongside PHQ-9
- The GAD-7 is an easy-to-use self-administered patient questionnaire used as a screening tool and severity measure for generalised anxiety disorder
Hospital Anxiety and Depression Scale (HADS)
- commonly used in research
- five-minute self-administered test suitable for use by a range of clinical professionals assessing emotional disorders in adults.
- used internationally, HADS is now available in 115 languages
- has cut-offs for clinical depression/anxiety
For those working at level 2 it is advised these measures are used and depending on the results referral to Level 3 or level 4 may be required.
At a specialist level (level 3) an initial assessment is conducted at the start of therapy. PHQ-9 and GAD-7 would be used as core outcome measures.
- There is also consideration around using the Work and Social Adjustment Scale (WSAS) and a process based measure (PsyFlex).
At a specialist level (level 4) an initial assessment is conducted at the start of therapy. PHQ-9 and GAD-7 would be used as core outcome measures. Level 4 practitioners have the skills to base assessment on individual situation and needs- further detail is outside the scope of this guidance.
- There is also consideration around using the Work and Social Adjustment Scale (WSAS) and a process based measure (PsyFlex).
Other difficulty/ symptom-based measures relevant to therapy (e.g., to assess for symptoms of PTSD or other psychological difficulties) and/or other process-based measures may be used as relevant. These are selected using an individualised, formulation-driven approach.
